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Multi-kinase Inhibitor

Flumatinib

Flumatinib is definitely a multi-kinase inhibitor with IC50 Principles of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRβ and c-Process respectively.

Relevant Goods: EP Z020411 2HCl

FAAH Inhibitor

BPF-04457845

BPF-04457845 is actually a highly efficacious and picky FAAH inhibitor with IC50 ideals is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, correspondingly.

Linked Products: LTI-291,Donepezil

SIRT6 Inhibitor

OSS128167

OSS128167 can be a particular SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, correspondingly.

Hooked up Merchandise: Quinine dihydrochloride

CRF1 Receptor Antagonist

CP 376395

CP 376395 is truly a highly effective and distinct Corticotropin providing factor 1 (CRF1) receptor antagonist.

Related Goods: GNE-617 , OSS128167

TMEM16A Inhibitor

CaCCinh-A01

CaCCinh-A01 is undoubtedly an inhibitor of both TMEM16A and calcium supplements-turned on chloride option (CaCC) with IC50s of 2.1 and 10 μM, respectively.

Hooked up Things: IPTG ,GNE-617

Products Catalog

Substance Nearby library

45 forms of ingredient libraries for high throughput evaluating and content evaluating.

Evaluation Areas

Proteases/Proteasome

Chromatin/Epigenetic

JAK/STAT signaling

Tyrosine Kinase/Adaptors

PI3K/Akt/mTOR Signaling

MAPK Signaling

Apotosis

Ubiquitination

Angiogenesis

Immunology/Discomfort

DNA Injuries/DNA Routine maintenance

See Much more…

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