IDO inhibitor
VX-11e Substance Platform NLG919
NLG919 is really a powerful IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with KiEC50 of 7 nM75 nM in cellular-price-cost-free assays. Period 1.
Associated Items Indoximod, INCB024360 analogue
TNF-α inhibitor
Trovirdine (LY-300046) Compound Structure CPI-1189
CPI-1189 (REN-1189) can be a TNF-α discharge inhibitor potentially for the treating of sciatica and postherpetic neuralgia.
Relevant Merchandise CX691 , Substance 4
Antiepileptic Medicine
DB07268 Substance Make up Valrocemide
Valrocemide (Television set-1901), is unquestionably an antiepileptic medicine (AED). Valrocemide contains a extensive range of anticonvulsant physical exercise and motivating possible becoming a new AED.
Attached Products Lvguidingan , NS 638
VEGFR Inhibitor
BML-210 Chemical Make up SU 5205
SU 5205 is in reality a VEGFR2 inhibitor.
Associated Products PF-CBP1 , SR-3029
PDGFR Inhibitor
AMG-337 Chemical Composition NSC 86429
NSC 86429, also called DMBI, is truly a potent and distinct inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are .8 and 19.4 μM respectively). SU4312 unexpectedly safeguards against MPP(+) -induced neurotoxicity via particular and fast inhibition of neuronal NOS.
Related Items I-CBP112 , GK921
IKr Course Blocker
JNJ-42165279 Compound Framework CK-1752
Sematilide, also known as CK-1752, is truly a institution III antiarrhythmic. It happens to be a discerning slowed rectifier K+ current (IKr) funnel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, contributing to the prolongation of motion probable span and refractoriness.
Pertinent Items XL-652 , WAY 200070
Product Catalog
Element Collection
45 kinds of component libraries for best throughput testing and written content evaluating.
Research Locations
ProteasesProteasome
ChromatinEpigenetic
JAKSTAT signaling
Tyrosine KinaseAdaptors
PI3KAktmTOR Signaling
MAPK Signaling
Apotosis
Ubiquitination
Angiogenesis
ImmunologyInflammation
DNA DamageDNA Resolve
UsTel 857-239-0968 Fax 857-239-8801
E-snail mail marketing and advertising@targetmol.com
Put 1 Boston Spot, Collection 2600, Boston, MA 02108.
One particular Boston Situation, Suite 2600, Boston, Massachusetts, 02108