Modest Components, Major Jobs

Cyclopamine  Ingredient ConstructionCyclopamine

Cyclopamine  is really a distinct Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 cellular materials.

Investigation stress: Becoming in touch with cyclopamine endorses pancreatic improvement in embryonic women. (Kim SK, et,al. PNAS, 1998, 95: 13036-13041.)

The piece can be purchased in : Bioactive Product Nearby assortment, Normal Ingredient Local community assortment

TWS119 Product or service FormulaTWS119

TWS119 is certainly a GSK-3β inhibitor with IC50 of 30 nM within the mobile-costs-free of cost assay competent at inducing neuronal differentiation and may also come in handy to will come transportable biology.

Analysis focus on: TWS119, a 4,6-disubstituted pyrrolopyrimidine that may induce neurogenesis in murine ESCs. (Ding S, et,al. PNAS, 2003,100(13): 7632-7637. )

The item contains in : Bioactive Chemical Catalog

Nicotinamide Compound FormulaNicotinamide

Nicotinamide (Supplement B3), a typical water to drink-soluble dietary, is surely an full of energy aspect of coenzymes NAD and NADP, in addition to serve as an activator of sirtuins.

Examination anxiety: nicotinamide enhanced the create of differentiation of Embryonic Can come Tissue to pancreatic endocrine tissues (Lumelsky N,et,al.Evaluation, 2001, 292(5520): 1389-1394 )

This technique characteristics in : Approved Drug Library, All-regular Compound Local community series

Affirmation libraries to distinguish a lot more functionally unique little resources!

Entails 3071 little molecule materials

A genuine assortment of 1700 accepted prescribed drugs

Features 640 standard ingredients

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