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Hot Materials in Protease Inhibitor In close proximity selection

MG-132

CAS No. 133407-82-6

MG-132 is without question an inhibitor of proteasome with IC50 of 100 nM in the cellphone-expense-free of charge assay, plus inhibits calpain with IC50 of 1.2 μM.

Bortezomib

CAS No. 179324-69-7

Bortezomib (PS-341) can be quite a successful 20S proteasome inhibitor with Ki of .6 nM in the cell mobile phone-price-cost-free assay.

Carfilzomib

CAS No. 868540-17-4

Carfilzomib (PR-171) is certainly an long term proteasome inhibitor with IC50 of 5 nM in ANBL-6 tissue, shown preferential in vitro inhibitory efficiency from the ChT-L exercising throughout the β5 subunit, but hardly any effect on the PGPH and T-L activities.

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